Hand over computer screen

Prof. Dr. Marianne Müller

Research Group Leader, Professor for Psychiatry and Psychotherapy University Medical Center of the Johannes Gutenberg-University Mainz

Kontakt

Leibniz-Institut für Resilienzforschung gGmbH
Hanns-Dieter-Hüsch-Weg 19
55128 Mainz

+49 (0)6131 39-30297
General Information
Year of Birth

1969

Current Position

Research Group Leader, Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Professor, Department of Psychiatry and Psychotherapy and Focus Program Translational Neurosciences (FTN), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

University training and degrees
01/1996

M.D. degree award (magna cum laude); Institute of Neuropathology, University of Bonn, Germany (supervisor: Prof. Dr. O.D. Wiestler)

10/1989 – 11/1995

Medical School, University of Bonn, Germany; speciality subject: Psychiatry (state examination 11/1995)

 

Advanced academic qualifications
11/2004

Privatdozentin (Habilitation); Venia Legendi in Psychiatry and Psychotherapy, Ludwig Maximilian University Munich, Germany

 

Postgraduate professional career
Since 01/2020

Research Group Leader and Head of Mouse Behaviour Unit (MBU) at the Leibniz Institute for Resilience Research (LIR), Mainz, Germany

Since 01/2018

Research Group Leader and Head of Mouse Behaviour Unit (MBU) at the German Resilience Center (DRZ) Mainz, Germany

Since 03/2014

Professor of Translational Psychiatry (permanent position), Head of Section Translational Psychiatry. University Medical Center of the Johannes Gutenberg University and Focus Program Translational Neuroscience, Mainz, Germany

01/2004 – 12/2013

Head, Independent Research Group Molecular Stress Physiology (Career breaks due to parental leave 02/2007 − 08/2007 and 08/2010 − 02/2011)

Since 2004

Minerva Program (Professorship Award/W2 for outstanding female scientists) from the Max Planck Society, Germany

01/2004 – 11/2007

Assistant Medical Director, Open Psychiatric Ward (Oberärztin)

12/2003

Board certification in Psychiatry (Fachärztin für Psychiatrie und Psychotherapie)

07/1996 – 12/2003

Residency in Psychiatry and Neurology; clinical training

04/1997 – 10/1997

Visiting scientist at the Netherlands Institute for Brain Research, Amsterdam, the Netherlands (supervisor: Prof. Dr. D.F. Swaab)

07/1996 – 12/2003

Postdoctoral Researcher, Molecular Neurogenetics Group (supervisor: Prof. Dr. W. Wurst)

01/1996 – 06/1996

Postdoctoral Fellow, Department of Neuropathology, University of Bonn Medical Center, Germany (supervisor: Prof. Dr. O. D. Wiestler)

Transparenz / Erklärung von Interessen

Frau Professorin Dr. Marianne Müller ist seit 2014 Professorin für Translationale Psychiatrie an der Universitätsmedizin Mainz und seit 2020 Arbeitsgruppenleiterin am Leibniz-Institut für Resilienzforschung. Sie hat seit 2018 keine persönlichen Honorare für Beratertätigkeiten, Fortbildungsveranstaltungen, Vorträge oder Stellungnahmen von pharmazeutischen Unternehmen oder Medizinprodukteherstellern erhalten. Von der gemeinnützigen Boehringer Ingelheim Stiftung erhielt Frau Professorin Müller gemeinsam mit anderen Wissenschaftlerinnen und Wissenschaftlern Forschungsmittel für die Jahre 2017-2020 zum Aufbau des Leibniz-Instituts für Resilienzforschung sowie von 2020 -2023 weitere Mittel zur Förderung der Kooperation mit der Universitätsmedizin Mainz.

Selected Publications

Herzog DP, Perumal N, Manicam C, Treccani G, Nadig J, Rossmanith M, Engelmann J, Jene T, Hasch A, van der Kooij MA, Lieb K, Gassen NC, Grus FH, Müller MB (2021). Longitudinal CSF proteome profiling in mice to uncover the acute and sustained mechanisms of action of rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK). Neurobiol Stress. 15:100404. doi: 10.1016/j.ynstr.2021.100404.

>> Link zu Pubmed

Jene T, Ruiz de Azua I, Hasch A, Klüpfel J, Deuster J, Maas M, Nijboer CH, Lutz B, Müller MB, van der Kooij M (2021). Chronic social stress lessens the metabolic effects induced by a high fat diet.
J Endocrinol. 2021 Feb:JOE-20-0633. doi: 10.1530/JOE-20-0633.

>> Link zu Pubmed

Lyons DM, Ayash S, Schatzberg AF, Müller MB (2023). Ecological validity of social defeat stressors in mouse models of vulnerability and resilience. Neurosci Biobehav Rev 145:105032 

>> Link zu Pubmed

Ruffini N, Müller M, Schmitt U, Gerber S (2021) IntelliPy: A GUI for analyzing IntelliCage data. Bioinformatics 37(21):3972–3. doi: 10.1093/bioinformatics/btab682. (Mitarbeiter AG Stroh) | IF 6,9 

>> Link zu Pubmed

Treccani G, Yigit H, Lingner T, Schleuβner V, Mey F, van der Kooij MA, Wennström M, Herzog DP, Linke M, Fricke M, Schmeisser MJ, Wegener G, Mittmann T, Trotter J, Müller MB (2021). Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (Na v) channels properties. Neurobiol Stress. 15:100338. doi: 10.1016/j.ynstr.2021.100338

>> Link zu Pubmed

van der Kooij MA, Rojas-Charry L, Givehchi M, Wolf C, Bueno D, Arndt S, Tenzer S, Mattioni L, Treccani G, Hasch A, Schmeisser MJ, Vianello C, Giacomello M, Methner A (2022). Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels. J Mol Med (Berl). 2022 Oct;100(10):1441-1453. doi: 10.1007/s00109-022-02235-x. Epub 2022 Aug 9. (Mitarbeiter/in AG Müller)

>> Link zu Pubmed

Wang M, Milic M, Gericke A, Mercieca K, Liu H, Ruan Y, Jiang S, van Beers T, von Pein HD, Müller MB, Prokosch V (2021). Chronic social defeat stress causes retinal vascular dysfunction. Exp Eye Res. 2021 Dec;213:108853. doi: 10.1016/j.exer.2021.108853. Epub 2021 Nov 18.

>> Link zu Pubmed

Yuan R, Nechvatal JM, Buckmaster CL, Ayash S, Parker KJ, Schatzberg AF, Lyons DM, Menon V (2021). Long-term effects of intermittent early life stress on primate prefrontal–subcortical functional connectivity. Neuropsychopharmacol. 2021 doi: 10.1038/s41386-021-00956-0

>> Link zu Pubmed
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